Allogeneic stem cell transplantation in X-linked lymphoproliferative disease: two cases in one family and review of the literature

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Allogeneic stem cell transplantation for advanced low-grade lymphoproliferative disorders: report of six cases.

BACKGROUND Allogeneic stem cell transplantation is being increasingly used to treat young patients with poor-prognosis low-grade lymphoproliferative disorders. We report our single-center experience. PATIENTS AND METHODS Six adults (four with advanced chronic lymphocytic leukemia, one follicular center cell lymphoma and one mantle cell lymphoma) underwent allogeneic stem cell transplantation ...

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X-Linked Lymphoproliferative Disease

2B4 is a surface molecule involved in activation of the natural killer (NK) cell-mediated cytotoxicity. It binds a protein termed Src homology 2 domain-containing protein (SH2D1A) or signaling lymphocyte activation molecule (SLAM)-associated protein (SAP), which in turn has been proposed to function as a regulator of the 2B4-associated signal transduction pathway. In this study, we analyzed pat...

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ژورنال

عنوان ژورنال: Bone Marrow Transplantation

سال: 2005

ISSN: 0268-3369,1476-5365

DOI: 10.1038/sj.bmt.1705016